The ArgumentIn Germany during the 1870s and 1880s a number of important scientific innovations in chemistry and biology emerged that were linked to advances in the new technology of synthetic dyestuffs. In particular, the rapid development of classical organic chemistry was a consequence of programs in which chemists devised new theories and experimental strategies that were applicable to the processes and products of the burgeoning dye factories. Thereafter, the novel products became the means to examine and measure biological systems. This (...) took place as a result of two trends. The first was a move toward diversification in the dye industry – made possible by the extensive range of products – which in turn was stimulated by economic and political conditions. The second was the increasing availability of techniques, substances, and processes used in industry. This made possible a concrete program of introducing the qualitative and quantitative methods of chemistry into the domain of laboratory experimentation on biological materials, thereby realizing the abstract desire to transform cell biology into an exact science.Moreover, the conceptualization of biological systems that emerged from this endeavor leaned heavily on a theory of dye chemistry that indicated which particular arrangements of atoms performed specific functions. This biological modeling used the imagery of chemical structural formulae to transform chemical nuclei and their side chains into adequate representations of protoplasmic structure. (shrink)

Raphael Meldola (1849-1915), an industrial chemist and keen naturalist, under the influence of Darwin, brought new German studies on evolution by natural selection that appeared in the 1870s to the attention of the British scientific community. Meldola's special interest was in mimicry among butterflies; through this he became a prominent neo-Darwinian. His wide-ranging achievements in science led to appointments as president of important professional scientific societies, and of a local club of like-minded amateurs, particularly field naturalists. This is an account (...) of Meldola's early scientific connections and studies related to entomology and natural selection, his contributions to the study of mimicry, and his promotion in the mid-1890s of a more theory driven approach among entomologists. (shrink)

In this second decade of the 21st century, we find the pervasive influence of synthetic biology everywhere, not only in research laboratories, but also in the discourses of politicians and ethicists. Despite its ubiquity, the precise meaning of the notions of "synthetic biology" and "synthetic life," as well as their history, potential, and risks, remain obscure not only to the layperson, but also to most biologists.The aim of this special issue is twofold. First, it is intended to help the reader (...) better appreciate what synthetic biology is all about and what are its roots. Second, once the overall picture has been expounded and made clearer, the questions of whether research in synthetic biology raises new and .. (shrink)

A familiar strategy of argument to the effect that natural-language predicates are semantically context dependent rests on constructing what I term Travis cases: different contexts for the use of a predicate are imagined in which its semantic (typically, truth-conditional) properties are claimed to differ. I propose an account of the semantic properties of predicates that give rise to Travis cases; I then argue that the account underwrites a genuine alternative to the standard explanations of Travis cases to (...) be found in the literature; I close with a brief sketch of the connections, required by a fuller development of my account, among the semantic notion of a predicate’s content, the metaphysical notion of a property’s instantiation, and the cognitive notion of a language user’s perspective in using a predicate. (shrink)

Until late in the nineteenth century, madder was the most popular natural red dye. Holland was the largest and best-known supplier. As early as the fourteenth and fifteenth centuries, the province of Zeeland and adjoining parts of the provinces of South Holland and Brabant developed into important producers. In the course of the seventeenth century these areas even succeeded in acquiring a monopoly position. Early in the nineteenth century, however, this position came under attack because France had gone over to (...) industrial production methods from around 1800, whereas Holland continued to produce with craft technologies. After 1820, as a result, a period of stagnation and decay set in. The fate of the Dutch madder industry would have been completely sealed if the production capacity of the French factories had been sufficiently large to satisfy the great increase in demand. Consequently, in Holland, after 1845, a process of revival based upon the French manufacturing methods began slowly and hesitatingly. This process started too late and was not persevered with sufficiently to regain lost markets. The Dutch producers remained strongly attached to their own out-dated, craft methods of production. (shrink)

way on the information available in the contexts in which they are used, it’s not surprising that there is a minor but growing industry of work in semantics and the philosophy of language concerned with the precise nature of the context-dependency of epistemically modalized sentences. Take, for instance, an epistemic might-claim like..

Counterfactuals are typically thought--given the force of Sobel sequences--to be variably strict conditionals. I go the other way. Sobel sequences and (what I call) Hegel sequences push us to a strict conditional analysis of counterfactuals: counterfactuals amount to some necessity modal scoped over a plain material conditional, just which modal being a function of context. To make this worth saying I need to say just how counterfactuals and context interact. No easy feat, but I have something to say on the (...) matter. (shrink)

What we want to be true about ordinary indicative conditionals seems to be more than we can possibly get: there just seems to be no good way to assign truth-conditions to ordinary indicative conditionals. Some take this argument as reason to make our wantings more modest. Others take it to show that indicative conditionals don't have truth-conditions in the first place. But we have overlooked two possibilities for assigning truth-conditions to indicatives. What's more, those possibilities deliver what we want and (...) turn out to be equivalent. CiteULike Connotea Del.icio.us Digg Reddit Technorati What's this? (shrink)

__Improvement in Action_, Anthony S. Bryk’s sequel to _Learning to Improve_, illustrates how educators have effectively applied the six core principles of continuous improvement in practice._ The book highlights relevant examples of rigorous, high-quality improvement work in districts, schools, and professional development networks across the country. The organizations featured in the book have addressed, with remarkable results, long-standing inequitable educational outcomes in high school graduation rates, college readiness, and absenteeism. The cases emphasize the measures the educators took and the (...) thinking that motivated their actions. Bryk describes how improvers, working in different contexts and confronting different problems, used select principles, tools, and methods to make improvement come to life. Brief analytic reflections are embedded throughout the narratives, and each chapter concludes with an analysis of a set of larger lessons illuminated by the organization’s story. Taken as a set, these examples offer readers valuable insights about the actual dynamics of doing improvement work. _Improvement in Action_, paired with _Learning to Improve_, provides readers with a comprehensive understanding of the practice, method, and theory of large-scale continuous improvement in education. (shrink)

This paper has three main goals. First, to motivate a puzzle about how ignorance-expressing terms like maybe and if interact: they iterate, and when they do they exhibit scopelessness. Second, to argue that there is an ambiguity in our theoretical toolbox, and that exposing that opens the door to a solution to the puzzle. And third, to explore the reach of that solution. Along the way, the paper highlights a number of pleasing properties of two elegant semantic theories, explores some (...) meta-theoretic properties of dynamic notions of meaning, dips its toe into some hazardous waters, and offers characterization theorems for the space of meanings an indicative conditional can have. (shrink)

An integrated statement is made concerning the semantic status of nodes in a propositional semantic network, claiming that such nodes represent only intensions. Within the network, the only reference to extensionality is via a mechanism to assert that two intensions have the same extension in same world. This framework is employed in three application problems to illustrate the nature of its solutions.The formalism used here utilizes only assertional information and no structural, or definitional, information. This restriction corresponds to many of (...) the psychologically motivated network models. Some of the psychological implications of network processes called node merging and node splitting are discussed. Additionally, it is pointed out that both our networks and the psychologically based networks are prone to memory confusions about knowing unless augmented by domain‐specific inference processes, or by structural information. (shrink)

A decade ago, the “new sociology of masculinity” emerged as an exciting new paradigm for understanding gender, emphasizing the study of “hegemonic power relations” among men and women. However, subsequent research has not fully redeemed the promise of the NSM, failing to seriously engage the theoretical implications of studying hegemony. This article addresses the lacunae by presenting a theoretically informed analysis of life history interviews with Chinese American men. Its chief empirical question is how Chinese American men “achieve” masculinity in (...) the face of negative stereotypes. This is accomplished, it is found, through four possible gender strategies: compensation, deflection, denial, or repudiation. The author then fashions a theoretical account of these strategies to show how they can reproduce the social order by striking a hegemonic bargain, which occurs when a Chinese American man's gender strategy involves consciously trading on—or unconsciously taking advantage of—the “privileges” of his race, gender, class, generation, and/or sexuality for the purposes of elevating his masculinity. (shrink)

Moore's paradox pits our intuitions about semantic oddnessagainst the concept of truth-functional consistency. Most solutions tothe problem proceed by explaining away our intuitions. But``consistency'' is a theory-laden concept, having different contours indifferent semantic theories. Truth-functional consistency is appropriateonly if the semantic theory we are using identifies meaning withtruth-conditions. I argue that such a framework is not appropriate whenit comes to analzying epistemic modality. I show that a theory whichaccounts for a wide variety of semantic data about epistemic modals(Update Semantics) buys (...) us a solution to Moore's paradox as a corollary.It turns out that Moorean propositions, when looked at through the lenseof an appropriate semantic theory, are inconsistent after all. (shrink)

Obligation describing language is hooked up with preference, a relation of what-is-better-than-what. But ordinary situations underdetermine such relations of what-is-better-than-what. Even so, there are plainly true sentences describing our obligations in those situations. This mismatch is trouble-making and getting out of the trouble requires either giving up the easy link between “ought” and preference or re-thinking the kind of things preferences can be.

This is a handbook article about conditionals.

Epistemic modals are standardly taken to be context-dependent quantifiers over possibilities. Thus sentences containing them get truth-values with respect to both a context and an index. But some insist that this relativization is not relative enough: `might'-claims, they say, only get truth-values with respect to contexts, indices, and—the new wrinkle—points of assessment (hence, CIA). Here we argue against such "relativist" semantics. We begin with a sketch of the motivation for such theories and a generic formulation of them. Then we catalogue (...) central problems that any such theory faces. We end by outlining an alternative story. (shrink)

It is a recurring mantra that epistemic must creates a statement that is weaker than the corresponding flat-footed assertion: It must be raining vs. It’s raining. Contrary to classic discussions of the phenomenon such as by Karttunen, Kratzer, and Veltman, we argue that instead of having a weak semantics, must presupposes the presence of an indirect inference or deduction rather than of a direct observation. This is independent of the strength of the claim being made. Epistemic must is therefore quite (...) similar to evidential markers of indirect evidence known from languages with rich evidential systems. We work towards a formalization of the evidential component, relying on a structured model of information states (analogous to some models used in the belief dynamics literature). We explain why in many contexts, one can perceive a lack of confidence on the part of the speaker who uses must. (shrink)

This comment on Alessandro Ferrara’s Democratic Horizon raises questions about his development of ‘conjectural reasoning’ and the democratic virtue of openness as responses to what he calls ‘hyperpluralism’. In order to probe these questions, the article offers an alternative reading of these ideas.

The simplest story about modals—might, must, possibly, necessary, have to, can, ought to, presumably, likelier, and the rest—is also the canon: modals are context-dependent quantifiers over a domain of possibilities. Different flavors of modality correspond to quantification over different domains of possibilities. Logical modalities quantify over all the possibilities there are, physical modalities over possibilities compatible with the..

John said, “Sam went to the bank”. He meant it as a literal statement to be assessed as true or false. He meant by “bank” ‘financial institution', referring by it to the First National Bank of Muncie. By “Sam” he referred to Sam Jorgensen. Do we need to know any other sorts of facts about John's utterance to know how it is to be understood?It might be argued that we do need to know something else, for suppose john produced an (...) utterance fitting the above description before Sam went to the bank. Then what he said was false. If John produced an utterance fitting the same description after Sam went to the bank, then what he said was true. Whatever John says on any occasion, it surely can't be both true and false. But if what John said before Sam went to the bank equals what john said after Sam went to the bank, equals what john said, then what john said appears to be both true and false. The moral drawn by this argument is that on the two different occasions john said two different things. So full specifications of what John would have said on the two different occasions must be different. These specifications must, then, differ by features not yet mentioned. (shrink)

We must change our beliefs, and change them in particular ways, in response to new information. But not all changes are created equal: some are rational changes, some not. The Problem of Epistemic Change is the problem of specifying the rational constraints on how the epistemic state of an agent ought to change in the face of new information. This dissertation is about the philosophical and logical investigation of rational belief change. I start by arguing that the familiar foundations---coherence distinction (...) from static epistemology does not adequately carve up the logical space of theories of epistemic change. It is better to think of theories as being loosely ordered along a continuum from more to less foundational. The ordering, however, is "clumpy" in the sense that there are large regions in the ordering which remain unexplored. I then present and develop GDEC which is a new foundations model of belief revision that fills a gap in this ordering of theories of epistemic change. The key insight in GDEC is that belief that...is ambiguous between the attitudes of accept that...and expect that... GDEC respects the difference and how it matters for epistemic change. I show that GDEC is a genuine competitor to the AGM theory of belief revision in the sense that the two approaches are incompatible. The remainder of the dissertation is devoted to exploring the logical dynamics of GDEC and the models I develop here which extend it by applying them to a series of richer epistemic environments. I show how puzzles and paradoxes which confound other theories of belief revision are solved in a unified way by GDEC and its extensions. In particular, I give solutions to Moore's Paradox, Fuhrmann's Impossibility Theorem, the Reduction Problem of Epistemic Conditionals, and the Gardenfors Impossibility Theorem. (shrink)

Mental health crisis has been reported as the third wave of the Covid-19 pandemic. Grief at the loss of loved ones, shock at the loss of jobs, isolation of restrictions of movements, difficult family dynamics, and uncertainty and fear of the future are just few of the psychological sufferings pointed out by the World Health Organization. To ensure that people are mentally healthy, the government takes mental health services as essential part of the responses to the pandemic. Private organizations and (...) academic institutions also take part in this movement to safeguard the mental well-being of people in the community. Despite the efforts to prevent and remediate mental health crisis, limited number of people seek professional help. While we can assume that they might have been adjusting well to the anxieties brought about by Covid-19 pandemic, we also acknowledge the fact that a number of cases of depression and suicide had been reported in the locality for the past five months. This paper aims to provide expositions of the possible variables for young Filipino College Students’ underutilization of mental health services as well as their other possible sources of inner strength and resiliency during the Covid-19 pandemic. Help seeking behaviors of the Young Filipino students in Cor Jesu College will be explored using the lens of uncertainty and anticipation model of anxiety of Grupe and Nitschke, and resilience as a cultural variable among Filipinos. (shrink)

Features of experimental design impose auxiliary hypotheses on experimenters. Hertwig & Ortmann rightly argue that the ways some variables are implemented in psychology cloud results, whereas the different implementations in economics provide for more robust results. However, not all design variables support this general conclusion. The repetition of trials may confuse results depending on what theory is being tested. We explore this in the case of simple bargaining games.

A novel method of teaching military medical ethics, medical ethics and military ethics in the Israel Defense Force (IDF) Medical Corps, essential topics for all military medical personnel, is discussed. Very little time is devoted to medical ethics in medical curricula, and even less to military medical ethics. Ninety-five per cent of American students in eight medical schools had less than 1 h of military medical ethics teaching and few knew the basic tenets of the Geneva Convention. Medical ethics differs (...) from military medical ethics: the former deals with the relationship between medical professional and patient, while in the latter military physicians have to balance between military necessity and their traditional priorities to their patients. The underlying principles, however, are the same in both: the right to life, autonomy, dignity and utility. The IDF maintains high moral and ethical standards. This stems from the preciousness of human life in Jewish history, tradition and religious law. Emphasis is placed on these qualities within the Israeli education system; the IDF teaches and enforces moral and ethical standards in all of its training programmes and units. One such programme is ‘Witnesses in Uniform’ in which the IDF takes groups of officers to visit Holocaust memorial sites and Nazi death camps. During these visits daily discussions touch on intricate medical and military ethical issues, and contemporary ethical dilemmas relevant to IDF officers during active missions. (shrink)

Male and female participants were instructed to produce an altered response pattern on an Implicit Association Test measure of gender identity by slowing performance in trials requiring the same response to stimuli designating own gender and self. Participants’ faking success was found to be predictable by a measure of slowing relative to unfaked performances. This combined task slowing (CTS) indicator was then applied in reanalyses of three experiments from other laboratories, two involving instructed faking and one involving possibly motivated faking. (...) Across all studies involving instructed faking, CTS correctly classified 75% of intentionally faking participants. Using the CTS index to adjust faked Implicit Association Test scores increased the correlation of CTS-adjusted measures with known group membership, relative to unadjusted (i.e., faked) measures. (shrink)

In "*Must* ...stay ...strong!" (von Fintel & Gillies 2010) we set out to slay a dragon, or rather what we called The Mantra: that epistemic *must* has a modal force weaker than expected from standard modal logic, that it doesn't entail its prejacent, and that the best explanation for the evidential feel of *must* is a pragmatic explanation. We argued that all three sub-mantras are wrong and offered an explanation according to which *must* is strong, entailing, and the felt indirectness (...) is the product of an evidential presupposition carried by epistemic modals. Mantras being what they are, it is no surprise that each of the sub-mantras have been given new defenses. Here we offer them new problems and update our picture, concluding that *must* is (still) strong. (shrink)

These are set against introductory essays describing the philosophical, historical and psychological approaches, making this a uniquely inclusive overview.

Assessment of decision-making capacity (DMC) can be difficult in acquired brain injury (ABI) particularly with the syndrome of organic personality disorder (OPD) (the “frontal lobe syndrome”). Clinical neuroscience may help but there are challenges translating its constructs to the decision-making abilities considered relevant by law and ethics. An in-depth interview study of DMC in OPD was undertaken. Six patients were purposefully sampled and rich interview data were acquired for scrutiny using interpretative phenomenological analysis. Interview data revealed that awareness of deficit (...) and thinking about psychological states can be present. However, the awareness of deficit may not be “online” and effectively integrated into decision-making. Without this online awareness of deficit the ability to appreciate or use and weigh information in the process of deciding some matters appeared absent. We argue that the decision-making abilities discussed are: (1) necessary for DMC, (2) threatened by ABI, and (3) assessable at interview. Some advice for practically incorporating these abilities within assessments of DMC in patients with OPD is outlined. (shrink)